Diminished spinal cord perfusion despite distal aortic perfusion: an acute translational large animal experiment with occluded segmental arteries
Josephina Haunschild, Zara Dietze, Susann Ossmann, Konstantin Von Aspern, Jörg Naumann, Michael A Borger, Christian D Etz

Affiliations Expand PMID: 39724192 DOI: 10.1093/ejcts/ezae460
Eur J Cardiothorac Surg 2024 Dec 26:ezae460. doi: 10.1093/ejcts/ezae460. Online ahead of print​​​​​​​

detectCilia: An R Package for Automated Detection and Length Measurement of Primary Cilia
Kai Budde-Sagert, Simone Krueger, Clemens Sehlke, Heiko Lemcke, Anika Jonitz-Heincke, Robert David, Rainer Bader, Adelinde M Uhrmacher
Affiliations Expand PMID: 39430098 PMCID: PMC11490958 DOI: 10.1177/11779322241280431

ChiSCAT: Unsupervised Learning of Recurrent Cellular Micromotion Patterns from a Chaotic Speckle Pattern.
Trelin A, Kussauer S, Weinbrenner P, Clasen A, David R, Rimmbach C, Reinhard F. Nano Lett. 2024 Sep 24. doi: 10.1021/acs.nanolett.4c02425. Online ahead of print. PMID: 39316755

Vascular Closure Devices For Axillary Artery Access: A Systematic Review and Meta-Analysis.
Koziarz A, Kennedy SA, Awad El-Karim G, Tan KT, Oreopoulos GD, Kalra S, Etz CD, Rajan DK, Mafeld S
J Endovasc Ther. 2024 Oct;31(5):763-771. doi: 10.1177/15266028221147451. Epub 2023 Jan 10.PMID: 36625294 Free PMC article. Review.

Clinical cases referring to the 2023 EACTS/STS Guidelines for diagnosing and treating acute and chronic syndromes of the aortic organ.
Czerny M, Berger T, Della Corte A, Kreibich M, Lescan M, Mestres CA, Quintana E, Rylski B, Schönhoff F; EACTS/STS Scientific Document Group; Czerny M, Grabenwöger M, Berger T, Aboyans V, Della Corte A, Chen EP, Desai N, Dumfarth J, Elefteriades JA, Etz CD, Kim KM, Kreibich M, Lescan M, Di Marco L, Martens A, Mestres CA, Milojevic M, Nienaber CA, Piffaretti G, Preventza O, Quintana E, Rylski B, Schlett CL, Schoenhoff F, Trimarchi S, Tsagakis K.Eur J Cardiothorac Surg. 2024 Sep 2;66(3):ezae294. doi: 10.1093/ejcts/ezae294.PMID: 39196761

Acute Aortic Dissection during Pregnancy: Hideous Clinical Quandaries with Young Lives on the Line-The Role of Hereditary Genetic Syndromes.
Haunschild J, Wiktorowska P, Eifert S, Stepan H, Dähnert I, Borger MA, Etz CD.J Clin Med. 2024 Aug 20;13(16):4901. doi: 10.3390/jcm13164901.PMID: 39201043 Free PMC article.

Frequent protein kinase A regulatory subunit A1 mutations but no GNAS mutations as potential driver in sporadic cardiac myxomas.
Zimpfer A, Abel LM, Alozie A, Etz CD, Schneider B.Cardiovasc Pathol. 2024 Jul-Aug;71:107632. doi: 10.1016/j.carpath.2024.107632. Epub 2024 Mar 15.PMID: 38492686 Free article.

EACTS/STS Guidelines for Diagnosing and Treating Acute and Chronic Syndromes of the Aortic Organ.
Authors/Task Force Members; Czerny M, Grabenwöger M, Berger T, Aboyans V, Della Corte A, Chen EP, Desai ND, Dumfarth J, Elefteriades JA, Etz CD, Kim KM, Kreibich M, Lescan M, Di Marco L, Martens A, Mestres CA, Milojevic M, Nienaber CA, Piffaretti G, Preventza O, Quintana E, Rylski B, Schlett CL, Schoenhoff F, Trimarchi S, Tsagakis K; EACTS/STS Scientific Document Group; Siepe M, Estrera AL, Bavaria JE, Pacini D, Okita Y, Evangelista A, Harrington KB, Kachroo P, Hughes GC.Ann Thorac Surg. 2024 Jul;118(1):5-115. doi: 10.1016/j.athoracsur.2024.01.021. Epub 2024 Feb 26.PMID: 38416090 No abstract available.

Intercellular pathways of cancer treatment-related cardiotoxicity and their therapeutic implications: The paradigm of radiotherapy.
Logotheti S, Pavlopoulou A, Rudsari HK, Galow AM, Kafali Y, Kyrodimos E, Giotakis AI, Marquardt S, Velalopoulou A, Verginadis II, Koumenis C, Stiewe T, Zoidakis J, Balasingham I, David R, Georgakilas AG.Pharmacol Ther. 2024 May 30:108670. doi: 10.1016/j.pharmthera.2024.108670. Online ahead of print.PMID: 38823489 Review.

Risk factors for long-term mortality after acute aortic dissection-results of the german registry for acute aortic dissection type a long-term follow-up.
Böning A, Kretzer JA, Arif R, Etz CD, Pöling J, Rylski B, Czerny M, Brickwedel J, Peterss S, Holubec T, Jawny P, Feißt M.
Eur J Cardiothorac Surg. 2024 Mar 26:ezae116. doi: 10.1093/ejcts/ezae116. Online ahead of print.PMID: 38530802

Frequent protein kinase A regulatory subunit A1 mutations but no GNAS mutations as potential driver in sporadic cardiac myxomas.
Zimpfer A, Abel LM, Alozie A, Etz CD, Schneider B.
Cardiovasc Pathol. 2024 Mar 14:107632. doi: 10.1016/j.carpath.2024.107632. Online ahead of print. PMID: 38492686

EACTS/STS Guidelines for diagnosing and treating acute and chronic syndromes of the aortic organ.
Czerny M, Grabenwöger M, Berger T, Aboyans V, Della Corte A, Chen EP, Desai ND, Dumfarth J, Elefteriades JA, Etz CD, Kim KM, Kreibich M, Lescan M, Di Marco L, Martens A, Mestres CA, Milojevic M, Nienaber CA, Piffaretti G, Preventza O, Quintana E, Rylski B, Schlett CL, Schoenhoff F, Trimarchi S, Tsagakis K;
EACTS/STS Scientific Document Group. Eur J Cardiothorac Surg. 2024 Feb 1;65(2):ezad426. doi: 10.1093/ejcts/ezad426. PMID: 38408364 No abstract available.

Heart rhythm in vitro: measuring stem cell-derived pacemaker cells on microelectrode arrays.
Kussauer S, Dilk P, Elleisy M, Michaelis C, Lichtwark S, Rimmbach C, David R, Jung J.
Front Cardiovasc Med. 2024 Feb 21;11:1200786. doi: 10.3389/fcvm.2024.1200786. eCollection 2024. PMID: 38450366 Free PMC article.

EACTS/STS Guidelines for Diagnosing and Treating Acute and Chronic Syndromes of the Aortic Organ.
Czerny M, Grabenwöger M, Berger T, Aboyans V, Della Corte A, Chen EP, Desai ND, Dumfarth J, Elefteriades JA, Etz CD, Kim KM, Kreibich M, Lescan M, Di Marco L, Martens A, Mestres CA, Milojevic M, Nienaber CA, Piffaretti G, Preventza O, Quintana E, Rylski B, Schlett CL, Schoenhoff F, Trimarchi S, Tsagakis K; EACTS/STS Scientific Document Group; Siepe M, Estrera AL, Bavaria JE, Pacini D, Okita Y, Evangelista A, Harrington KB, Kachroo P, Hughes GC.
Ann Thorac Surg. 2024 Feb 22:S0003-4975(24)00077-8. doi: 10.1016/j.athoracsur.2024.01.021. Online ahead of print. PMID: 38416090 No abstract available.

Multi-modal assessment of a cardiac stem cell therapy reveals distinct modulation of regional scar properties.
Schweins M, Gäbel R, Raitza M, Vasudevan P, Lemcke H, Joksch M, Schildt A, Kurth J, Lindner T, Meinel FG, Öner A, Ince H, Vollmar B, Krause BJ, David R, Lang CI.
J Transl Med. 2024 Feb 21;22(1):187. doi: 10.1186/s12967-024-04986-2. PMID: 38378655

The Frozen Elephant Technique Using a Novel Hybrid Prosthesis for Extensive Aortic Arch Disease: A Multicentre Study.
El-Sayed Ahmad A, Silaschi M, Borger M, Seidiramool V, Hamiko M, Leontyev S, Zierer A, Doss M, Etz CD, Benedikt P, Bramlage P, Bakhtiary F.
Adv Ther. 2023 Mar;40(3):1104-1113. doi: 10.1007/s12325-022-02418-5. Epub 2023 Jan 12. PMID: 36633731 Free PMC article.

Is perioperative fast-track management the future of proximal aortic repair?
Haunschild J, van Kampen A, Misfeld M, Von Aspern K, Ender J, Zakhary W, Borger MA, Etz CD.
Eur J Cardiothorac Surg. 2023 Feb 3;63(2):ezac578. doi: 10.1093/ejcts/ezac578. PMID: 36538944 Review.

Vascular Closure Devices For Axillary Artery Access: A Systematic Review and Meta-Analysis.
Koziarz A, Kennedy SA, Awad El-Karim G, Tan KT, Oreopoulos GD, Kalra S, Etz CD, Rajan DK, Mafeld S.
J Endovasc Ther. 2023 Jan 10:15266028221147451. doi: 10.1177/15266028221147451. Online ahead of print. PMID: 36625294 Free article. Review.

The correlation of age and extension length in DeBakey type I aortic dissection: are older patients over 70 years at a lower risk?
Merkle-Storms J, Gaisendrees C, Feisst M, Rylski B, Dohle DS, Hagl C, Lescan M, Brickwede J, Poeling J, Holubec T, Etz CD, Jawny P, Noack T, Arif R, Wahlers T, Boening A, Luehr M.
Eur J Cardiothorac Surg. 2023 Jun 1;63(6):ezad175. doi: 10.1093/ejcts/ezad175. PMID: 37104742

Abdominal Aortic Endograft Implantation Immediately Induces Vascular Stiffness Gradients That May Promote Adverse Aortic Neck Dilatation: Results of A Porcine Ex Vivo Study.
Schellinger IN, Naumann J, Hoffmann A, Barnard SJ, Düsing S, Wagenhäuser MU, Haunschild J, Scheinert D, Hasenfuß G, Etz CD, Raaz U.
J Endovasc Ther. 2023 May 8:15266028231169178. doi: 10.1177/15266028231169178. Online ahead of print. PMID: 37154344 Free article.

Apoptotic Cell Death in Bicuspid-Aortic-Valve-Associated Aortopathy.
Barnard SJ, Haunschild J, Heiser L, Dieterlen MT, Klaeske K, Borger MA, Etz CD.
Int J Mol Sci. 2023 Apr 18;24(8):7429. doi: 10.3390/ijms24087429. PMID: 37108591 Free PMC article.

Minimally invasive staged segmental artery coil embolization (MIS²ACE) for spinal cord protection.
Haunschild J, Köbel T, Misfeld M, Etz CD.
Ann Cardiothorac Surg. 2023 Sep 28;12(5):492-499. doi: 10.21037/acs-2023-scp-21. Epub 2023 Sep 19. PMID: 37817850 Free PMC article.

Hormone substitution as abates inflammation-is clinical implementation yet indicated?
Haunschild J, Etz CD.
Eur J Cardiothorac Surg. 2023 Sep 7;64(3):ezad303. doi: 10.1093/ejcts/ezad303. PMID: 37707620 No abstract available.

Early Intraluminal Frozen Elephant Trunk Stent Graft Thrombosis After Aortic Arch Surgery.
Misfeld M, Marin-Cuartas M, Ramirez P, Wehrmann K, Renatus K, Deo SV, Gohmann RF, Haunschild J, Leontyev S, Borger MA, Etz CD.
Ann Thorac Surg. 2023 Sep;116(3):450-457. doi: 10.1016/j.athoracsur.2022.12.030. Epub 2023 Jan 4. PMID: 36608753

Sarcomeric network analysis of ex vivo cultivated human atrial appendage tissue using super-resolution microscopy.
Chabanovska O, Lemcke H, Lang H, Vollmar B, Dohmen PM, David R, Etz C, Neßelmann C.
Sci Rep. 2023 Aug 10;13(1):13041. doi: 10.1038/s41598-023-39962-1. PMID: 37563225 Free PMC article.

Bilateral Axillary Artery Perfusion for Aortic Arch Surgery: Worth the Effort?
Etz CD, Borger MA.
Ann Thorac Surg. 2023 Jul;116(1):42. doi: 10.1016/j.athoracsur.2022.11.029. Epub 2022 Dec 5. PMID: 36470564 No abstract available.

Aortic arch redo surgery: early and mid-term outcomes in 120 patients.
Dietze Z, Kang J, Madomegov K, Etz CD, Misfeld M, Borger MA, Leontyev S.
Eur J Cardiothorac Surg. 2023 Dec 1;64(6):ezad419. doi: 10.1093/ejcts/ezad419. PMID: 38109680

Sex-Related Differences After Proximal Aortic Surgery: Outcome Analysis of 1773 Consecutive Patients.
van Kampen A, Haunschild J, von Aspern K, Dietze Z, Misfeld M, Saeed D, Borger MA, Etz CD.
Ann Thorac Surg. 2023 Dec;116(6):1186-1193. doi: 10.1016/j.athoracsur.2022.05.039. Epub 2022 Jun 10. PMID: 35697115

The Feasibility of Less-Invasive Bentall Surgery: A Real-World Analysis.
van Kampen A, Etz CD, Haunschild J, Misfeld M, Davierwala P, Leontyev S, Borger MA.
Life (Basel). 2023 Nov 13;13(11):2204. doi: 10.3390/life13112204. PMID: 38004345 Free PMC article.

Near-Infrared Spectroscopy for Spinal Cord Monitoring-A Roadmap to Translational Research in Aortic Medicine.
von Aspern K, Haunschild J, Garbade J, Etz CD.
Aorta (Stamford). 2023 Nov 10. doi: 10.1055/s-0043-1772774. Online ahead of print. PMID: 37949108 Free article.

Rationale of the PAPAartis trial.
Misfeld M, Haunschild J, Petroff D, Borger MA, Etz CD.
Ann Cardiothorac Surg. 2023 Sep 28;12(5):463-467. doi: 10.21037/acs-2023-scp-0062. Epub 2023 Sep 4. PMID: 37817856 Free PMC article. Review.

BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice.
Cattaneo M, Aleksova A, Malovini A, Avolio E, Thomas A, Alvino VV, Kilcooley M, Pieronne-Deperrois M, Ouvrard-Pascaud A, Maciag A, Spinetti G, Kussauer S, Lemcke H, Skorska A, Vasudevan P, Castiglione S, Raucci A, David R, Richard V, Beltrami AP, Madeddu P, Puca AA.
Cell Death Dis. 2023 Aug 15;14(8):523. doi: 10.1038/s41419-023-06011-8. PMID: 37582912 Free PMC article.

CCR2 macrophage response determines the functional outcome following cardiomyocyte transplantation.
Vasudevan P, Wolfien M, Lemcke H, Lang CI, Skorska A, Gaebel R, Galow AM, Koczan D, Lindner T, Bergmann W, Mueller-Hilke B, Vollmar B, Krause BJ, Wolkenhauer O, Steinhoff G, David R.
Genome Med. 2023 Aug 10;15(1):61. doi: 10.1186/s13073-023-01213-3. PMID: 37563727 Free PMC article.

Sarcomeric network analysis of ex vivo cultivated human atrial appendage tissue using super-resolution microscopy.
Chabanovska O, Lemcke H, Lang H, Vollmar B, Dohmen PM, David R, Etz C, Neßelmann C.
Sci Rep. 2023 Aug 10;13(1):13041. doi: 10.1038/s41598-023-39962-1. PMID: 37563225 Free PMC article.

Cardiac cell therapies for the treatment of acute myocardial infarction in mice: systematic review and meta-analysis.
Lang CI, Dahmen A, Vasudevan P, Lemcke H, Gäbel R, Öner A, Ince H, David R, Wolfien M.
Cytotherapy. 2023 Jun;25(6):640-652. doi: 10.1016/j.jcyt.2023.01.013. Epub 2023 Mar 6. PMID: 36890093

New Approaches in Heart Research: Prevention Instead of Cardiomyoplasty?
Gaebel R, Lang C, Vasudevan P, Lührs L, de Carvalho KAT, Abdelwahid E, David R.
Int J Mol Sci. 2023 May 19;24(10):9017. doi: 10.3390/ijms24109017. PMID: 37240361 Free PMC article. Review.

Cell Programming for Cardiovascular Disease Modeling and Therapy.
David R.
Int J Mol Sci. 2023 Apr 26;24(9):7877. doi: 10.3390/ijms24097877. PMID: 37175582 Free PMC article.

The versatile role of the contact system in cardiovascular disease, inflammation, sepsis and cancer.
Oehmcke-Hecht S, Berlin P, Müller-Hilke B, Kreikemeyer B, Vasudevan P, Henze L, Khaimov V, Vollmar B, David R, Maletzki C.
Biomed Pharmacother. 2022 Jan;145:112429. doi: 10.1016/j.biopha.2021.112429. Epub 2021 Nov 18. PMID: 34801854 Free article. Review.

Monitoring the maturation of the sarcomere network: a super-resolution microscopy-based approach.
Skorska A, Johann L, Chabanovska O, Vasudevan P, Kussauer S, Hillemanns M, Wolfien M, Jonitz-Heincke A, Wolkenhauer O, Bader R, Lang H, David R, Lemcke H.
Cell Mol Life Sci. 2022 Feb 23;79(3):149. doi: 10.1007/s00018-022-04196-3. PMID: 35199227 Free PMC article.

The Effects of Hypoxic Preconditioned Murine Mesenchymal Stem Cells on Post-Infarct Arrhythmias in the Mouse Model.
Ahmad B, Skorska A, Wolfien M, Sadraddin H, Lemcke H, Vasudevan P, Wolkenhauer O, Steinhoff G, David R, Gaebel R.
Int J Mol Sci. 2022 Aug 9;23(16):8843. doi: 10.3390/ijms23168843. PMID: 36012110 Free PMC article.

Long-Term Follow-Up of Mechanical Circulatory Support in Peripartum Cardiomyopathy (PPCM) Refractory to Medical Management: A Multicenter Study.
Jawad K, Koziarz A, Dieterlen MT, Garbade J, Etz CD, Saeed D, Langer E, Stepan H, Scholz U, Krause M, Brenner P, Schulz U, Borger MA, Eifert S.
Life (Basel). 2022 Jan 7;12(1):87. doi: 10.3390/life12010087. PMID: 35054480 Free PMC article.

Supracommissural replacement of the ascending aorta and the aortic valve via partial versus full sternotomy-a propensity-matched comparison in a high-volume centre.
Haunschild J, van Kampen A, von Aspern K, Misfeld M, Davierwala P, Saeed D, Borger MA, Etz CD.
Eur J Cardiothorac Surg. 2022 Jan 24;61(2):479-487. doi: 10.1093/ejcts/ezab373. PMID: 34453828

Left ventricular assist device implants in patients on extracorporeal membrane oxygenation: do we need cardiopulmonary bypass?
Pappalardo F, Potapov E, Loforte A, Morshuis M, Schibilsky D, Zimpfer D, Riebandt J, Etz C, Attisani M, Rinaldi M, Haneya A, Ramjankhan F, Donker D, Jorde UP, Lewin D, Wieloch R, Ayala R, Cremer J, Bertoldi L, Borger M, Lichtenberg A, Gummert J, Saeed D;
Durable MCS after ECLS study group. Interact Cardiovasc Thorac Surg. 2022 Mar 31;34(4):676-682. doi: 10.1093/icvts/ivab311. PMID: 34788423 Free PMC article.

Tricuspid valve repair with echocardiographic guiding.
Pfannmueller B, Noack T, Etz CD, Borger MA, Ender J, Flo Forner A.
J Cardiovasc Surg (Torino). 2022 Apr;63(2):208-211. doi: 10.23736/S0021-9509.21.11910-X. Epub 2021 Jul 26. PMID: 34308614

Perioperative temporary mechanical circulatory support with Impella in cardiac surgery patients.
Marin-Cuartas M, Wehrmann K, Höbartner M, Lehmann S, Etz CD, Saeed D, Borger MA.
J Cardiovasc Surg (Torino). 2022 Apr;63(2):229-236. doi: 10.23736/S0021-9509.22.12173-7. Epub 2022 Feb 10. PMID: 35142461

Ischemic Spinal Cord Injury-Experimental Evidence and Evolution of Protective Measures.
Khachatryan Z, Haunschild J, von Aspern K, Borger MA, Etz CD.
Ann Thorac Surg. 2022 May;113(5):1692-1702. doi: 10.1016/j.athoracsur.2020.12.028. Epub 2021 Jan 9. PMID: 33434541 Review.

Mapping the collateral network: Optimal near-infrared spectroscopy optode placement.
von Aspern K, Haunschild J, Khachatryan Z, Simoniuk U, Ossmann S, Borger MA, Etz CD.
J Thorac Cardiovasc Surg. 2022 Jul;164(1):e3-e15. doi: 10.1016/j.jtcvs.2020.07.103. Epub 2020 Aug 11. PMID: 32893012

Aortic root replacement in bicuspid versus tricuspid aortic valve patients.
Haunschild J, Dietze Z, van Kampen A, Magomedov K, Misfeld M, Leontyev S, Borger MA, Etz CD.
Ann Cardiothorac Surg. 2022 Jul;11(4):436-447. doi: 10.21037/acs-2022-bav-67. PMID: 35958530 Free PMC article.

The aortic team and bicuspid aortic valve patients.
Misfeld M, Etz CD, Leontyev S, Borger MA.
Ann Cardiothorac Surg. 2022 Jul;11(4):459-461. doi: 10.21037/acs-2021-bav-213. PMID: 35958534 Free PMC article. No abstract available.

Management of anomalous coronary anatomy during aortic valve repair.
Davierwala PM, Khan I, Etz C, Borger MA.
Ann Cardiothorac Surg. 2022 Jul;11(4):487-489. doi: 10.21037/acs-2022-bav-25. PMID: 35958536 Free PMC article. No abstract available.

Technical feasibility of three-dimensional rotational angiography during experimental minimally invasive segmental artery occlusion.
von Aspern K, Haunschild J, Garbade J, Borger MA, Etz CD.
J Cardiovasc Surg (Torino). 2022 Aug;63(4):536-537. doi: 10.23736/S0021-9509.22.12312-8. Epub 2022 Apr 7. PMID: 35389040 Free article. No abstract available.

Iatrogenic Type A Aortic Dissection: Challenges and Frontiers-Contemporary Single Center Data and Clinical Perspective.
von Aspern K, Leontyev S, Etz CD, Haunschild J, Misfeld M, Borger MA.
Aorta (Stamford). 2022 Aug;10(4):201-209. doi: 10.1055/s-0042-1756670. Epub 2022 Dec 15. PMID: 36521814 Free PMC article.

Effects of fluids vs. vasopressors on spinal cord microperfusion in hemorrhagic shock induced ischemia/reperfusion.
Behem CR, Haunschild J, Pinnschmidt HO, Gaeth C, Graessler MF, Trepte CJC, Etz CD, Debus ES, Wipper SH.
Microvasc Res. 2022 Sep;143:104383. doi: 10.1016/j.mvr.2022.104383. Epub 2022 May 20. PMID: 35605693

There is nothing better than participating in this study": Living the PAPAartis cardiovascular randomised controlled trial.
Romo-Avilés N, Zapata JF, Keuneke A, Petroff D, Etz CD, Epstein D.
Contemp Clin Trials Commun. 2022 Sep 3;29:100987. doi: 10.1016/j.conctc.2022.100987. eCollection 2022 Oct. PMID: 36111175 Free PMC article.

Impact of distal aortic perfusion on 'segmental steal' depleting spinal cord blood flow-a quantitative experimental approach.
Haunschild J, von Aspern K, Herajärvi J, Dietze Z, Naumann J, Ossmann S, Misfeld M, Borger MA, Etz CD.
Eur J Cardiothorac Surg. 2022 Oct 4;62(5):ezac213. doi: 10.1093/ejcts/ezac213. PMID: 35441230

Single-Cell RNA Sequencing Procedures and Data Analysis
Markus Wolfien, Robert David, Anne-Marie Galow, Nakaya Helder
Bioinformatics [Internet]. Brisbane (AU): Exon Publications; 2021 Mar 20 PMID: 33877763 Bookshelf ID: NBK569559 DOI: 10.36255/exonpublications.bioinformatics.2021

Expedient assessment of post-infarct remodeling by native cardiac magnetic resonance imaging in mice
Cajetan Immanuel Lang, Praveen Vasudevan, Piet Döring, Ralf Gäbel, Heiko Lemcke, Tobias Lindner, Gustav Steinhoff, Bernd Joachim Krause, Brigitte Vollmar, Felix G Meinel, Seyrani Yücel, Alper Öner, Hüseyin Ince, Robert David
Comparative Study Sci Rep. 2021 Jun 2;11(1):11625. doi: 10.1038/s41598-021-91096-4. PMID: 34079005 PMCID: PMC8172884

Quality control in scRNA-Seq can discriminate pacemaker cells: the mtRNA bias.
Galow AM, Kussauer S, Wolfien M, Brunner RM, Goldammer T, David R, Hoeflich A.
Cell Mol Life Sci. 2021 Oct;78(19-20):6585-6592. doi: 10.1007/s00018-021-03916-5. Epub 2021 Aug 24. PMID: 34427691 Free PMC article

Automated annotation of rare-cell types from single-cell RNA-sequencing data through synthetic oversampling.
Bej S, Galow AM, David R, Wolfien M, Wolkenhauer O.
BMC Bioinformatics. 2021 Nov 19;22(1):557. doi: 10.1186/s12859-021-04469-x. PMID: 34798805 Free PMC article.

mRNA - A game changer in regenerative medicine, cell-based therapy and reprogramming strategies.
Chabanovska O, Galow AM, David R, Lemcke H.
Adv Drug Deliv Rev. 2021 Dec;179:114002. doi: 10.1016/j.addr.2021.114002. Epub 2021 Oct 13. PMID: 34653534 Free PMC article. Review.

The versatile role of the contact system in cardiovascular disease, inflammation, sepsis and cancer.
Oehmcke-Hecht S, Berlin P, Müller-Hilke B, Kreikemeyer B, Vasudevan P, Henze L, Khaimov V, Vollmar B, David R, Maletzki C.
Biomed Pharmacother. 2022 Jan;145:112429. doi: 10.1016/j.biopha.2021.112429. Epub 2021 Nov 18. PMID: 34801854 Free article. Review.

The Ross sub-coronary technique.
Misfeld M, Etz CD, Borger MA, Sievers HH.
Ann Cardiothorac Surg. 2021 Jul;10(4):538-540. doi: 10.21037/acs-2020-rp-184.PMID: 34422570

Anatomical description of the intraspinal collateral network: bringing the concept full circle-is the devil in the details?
von Aspern K, Haunschild J, Borger MA, Etz CD.
Eur J Cardiothorac Surg. 2021 Jan 4;59(1):144-146. doi: 10.1093/ejcts/ezaa341. PMID: 32944743 No abstract available.

The Angiogenic Potential of Mesenchymal Stem Cells from the Hair Follicle Outer Root Sheath.
Savkovic V, Li H, Obradovic D, Masieri FF, Bartella AK, Zimmerer R, Simon JC, Etz C, Lethaus B.
J Clin Med. 2021 Feb 26;10(5):911. doi: 10.3390/jcm10050911. PMID: 33652691 Free PMC article.

Mechanical circulatory support for early surgical repair of postinfarction ventricular septal defect with cardiogenic shock.
Vondran M, Wehbe MS, Etz C, Ghazy T, Rastan AJ, Borger MA, Schroeter T.
Artif Organs. 2021 Mar;45(3):244-253. doi: 10.1111/aor.13808. Epub 2020 Oct 27. PMID: 32857884

Management of aortic root in type A dissection: Bentall approach.
Khachatryan Z, Leontyev S, Magomedov K, Haunschild J, Holzhey DM, Misfeld M, Etz CD, Borger MA.
J Card Surg. 2021 May;36(5):1779-1785. doi: 10.1111/jocs.15271. Epub 2020 Dec 20. PMID: 33345377

Spinal cord monitoring using collateral network near-infrared spectroscopy during extended aortic arch surgery with a frozen elephant trunk.
von Aspern K, Sgouropoulou S, Davierwala P, Borger MA, Etz CD.
J Surg Case Rep. 2021 May 8;2021(5):rjab174. doi: 10.1093/jscr/rjab174. eCollection 2021 May. PMID: 33981408 Free PMC article.

Propensity score matched comparison of isolated, elective aortic valve replacement with and without concomitant septal myectomy: is it worth it?
von Aspern K, Bianchi E, Haunschild J, Dahlenburg C, Misfeld M, Borger MA, Etz CD.
J Cardiovasc Surg (Torino). 2021 Jun;62(3):258-267. doi: 10.23736/S0021-9509.20.11443-5. Epub 2020 Sep 4. PMID: 32885927

European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria.
Biancari F, Mariscalco G, Yusuff H, Tsang G, Luthra S, Onorati F, Francica A, Rossetti C, Perrotti A, Chocron S, Fiore A, Folliguet T, Pettinari M, Dell'Aquila AM, Demal T, Conradi L, Detter C, Pol M, Ivak P, Schlosser F, Forlani S, Chetty G, Harky A, Kuduvalli M, Field M, Vendramin I, Livi U, Rinaldi M, Ferrante L, Etz C, Noack T, Mastrobuoni S, De Kerchove L, Jormalainen M, Laga S, Meuris B, Schepens M, El Dean Z, Vento A, Raivio P, Borger M, Juvonen T.
J Cardiothorac Surg. 2021 Jun 10;16(1):171. doi: 10.1186/s13019-021-01536-5. PMID: 34112230 Free PMC article.

Comparison of periodontal parameters between patients with ischemic and dilative cardiomyopathy.
Ziebolz D, Binner C, Reuschel F, Eisner M, Wagner J, Kottmann T, Etz CD, Lehmann S, Garbade J, Schmalz G.
BMC Cardiovasc Disord. 2021 Jun 16;21(1):304. doi: 10.1186/s12872-021-02111-5. PMID: 34134635 Free PMC article.

The Ross sub-coronary technique.
Misfeld M, Etz CD, Borger MA, Sievers HH.
Ann Cardiothorac Surg. 2021 Jul;10(4):538-540. doi: 10.21037/acs-2020-rp-184. PMID: 34422570 Free PMC article. No abstract available.

Experimental near-infrared spectroscopy-guided minimally invasive segmental artery occlusion.
von Aspern K, Haunschild J, Heier M, Ossmann S, Mohr FW, Borger MA, Etz CD.
Eur J Cardiothorac Surg. 2021 Jul 14;60(1):48-55. doi: 10.1093/ejcts/ezab005. PMID: 33538301

Magnetic resonance imaging in patients with postoperative spinal cord injury: 'one step at a time towards safer aortic repair'.
von Aspern K, Borger MA, Etz CD.
Eur J Cardiothorac Surg. 2021 Jul 14;60(1):174-176. doi: 10.1093/ejcts/ezab062. PMID: 33580668 No abstract available.

Proximal aortic aneurysms: correlation of maximum aortic diameter and aortic wall thickness.
Haunschild J, Barnard SJ, Misfeld M, Saeed D, Davierwala P, Leontyev S, Mende M, Borger MA, Etz CD.
Eur J Cardiothorac Surg. 2021 Jul 30;60(2):322-330. doi: 10.1093/ejcts/ezab147. PMID: 33822923

Gender-related differences in patients with acute aortic dissection type A.
Rylski B, Georgieva N, Beyersdorf F, Büsch C, Boening A, Haunschild J, Etz CD, Luehr M, Kallenbach K;
German Registry for Acute Aortic Dissection Type A Working Group of the German Society of Thoracic, Cardiac, and Vascular Surgery. J Thorac Cardiovasc Surg. 2021 Aug;162(2):528-535.e1. doi: 10.1016/j.jtcvs.2019.11.039. Epub 2019 Nov 27. PMID: 31926709 Free article.

Spinal cord protection in thoracoabdominal aortic aneurysm surgery: a multimodal approach.
Haunschild J, VON Aspern K, Misfeld M, Davierwala P, Borger MA, Etz CD.
J Cardiovasc Surg (Torino). 2021 Aug;62(4):316-325. doi: 10.23736/S0021-9509.21.11783-5. Epub 2021 Jan 26. PMID: 33496426 Free article. Review.

Correction to: European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria.
Biancari F, Mariscalco G, Yusuff H, Tsang G, Luthra S, Onorati F, Francica A, Rossetti C, Perrotti A, Chocron S, Fiore A, Folliguet T, Pettinari M, Dell'Aquila AM, Demal T, Conradi L, Detter C, Pol M, Ivak P, Schlosser F, Forlani S, Chetty G, Harky A, Kuduvalli M, Field M, Vendramin I, Livi U, Rinaldi M, Ferrante L, Etz C, Noack T, Mastrobuoni S, De Kerchove L, Jormalainen M, Laga S, Meuris B, Schepens M, Dean ZE, Vento A, Raivio P, Borger M, Juvonen T.
J Cardiothorac Surg. 2021 Aug 9;16(1):225. doi: 10.1186/s13019-021-01606-8. PMID: 34365965 Free PMC article. No abstract available.

Effect of cerebrospinal fluid pressure elevation on spinal cord perfusion during aortic cross-clamping with distal aortic perfusion.
Haunschild J, Khachatryan Z, von Aspern K, Herajärvi J, Ossmann S, Naumann J, Borger MA, Etz CD.
Eur J Cardiothorac Surg. 2021 Sep 11;60(3):569-576. doi: 10.1093/ejcts/ezab167. PMID: 33839764

Mid-term results after isolated tricuspid valve surgery in the presence of right ventricular leads.
Pfannmueller B, Budde LM, Etz CD, Noack T, Marin-Cuartas M, Misfeld M, Borger MA.
J Cardiovasc Surg (Torino). 2021 Oct;62(5):510-514. doi: 10.23736/S0021-9509.21.11803-8. Epub 2021 Apr 8. PMID: 33829746

Postoperative outcome after reoperative isolated tricuspid valve surgery-is there a predictor for survival?
Pfannmueller B, Budde LM, Etz CD, Noack T, Cuartas MM, Misfeld M, Borger MA.
Eur J Cardiothorac Surg. 2021 Oct 22;60(4):867-871. doi: 10.1093/ejcts/ezab134. PMID: 33769458

Differential Regulation of Myocardial E3 Ligases and Deubiquitinases in Ischemic Heart Failure.
Klaeske K, Dix M, Adams V, Jawad K, Eifert S, Etz C, Saeed D, Borger MA, Dieterlen MT.
Life (Basel). 2021 Dec 18;11(12):1430. doi: 10.3390/life11121430. PMID: 34947961 Free PMC article.

Analyzing the α-Actinin Network in Human iPSC-Derived Cardiomyocytes Using Single Molecule Localization Microscopy.
Johann L, Chabanovska O, Lang CI, David R, Lemcke H.
J Vis Exp. 2020 Nov 3;(165). doi: 10.3791/61605.PMID: 33226020

Continuous Electrical Stimulation Affects Initial Growth and Proliferation of Adipose-Derived Stem Cells.
Kämmerer PW, Engel V, Plocksties F, Jonitz-Heincke A, Timmermann D, Engel N, Frerich B, Bader R, Thiem DGE, Skorska A, David R, Al-Nawas B, Dau M.
Biomedicines. 2020 Nov 8;8(11):482. doi: 10.3390/biomedicines8110482.PMID: 33171654 Free PMC article.

Cardiomyocyte Transplantation after Myocardial Infarction Alters the Immune Response in the Heart.
Vasudevan P, Wolfien M, Lemcke H, Lang CI, Skorska A, Gaebel R, Koczan D, Lindner T, Engelmann R, Vollmar B, Krause BJ, Wolkenhauer O, Lang H, Steinhoff G, David R.
Cells 2020 Aug 3;9(8):E1825.

Hematopoietic stem-cell senescence and myocardial repair - Coronary artery disease genotype/phenotype analysis of post-MI myocardial regeneration response induced by CABG/CD133+ bone marrow hematopoietic stem cell treatment in RCT PERFECT Phase 3.
Wolfien M, Klatt D, Salybekov AA, Ii M, Komatsu-Horii M, Gaebel R, Philippou-Massier J, Schrinner E, Akimaru H, Akimaru E, David R, Garbade J, Gummert J, Haverich A, Hennig H, Iwasaki H, Kaminski A, Kawamoto A, Klopsch C, Kowallick JT, Krebs S, Nesteruk J, Reichenspurner H, Ritter C, Stamm C, Tani-Yokoyama A, Blum H, Wolkenhauer O, Schambach A, Asahara T, Steinhoff G.
EBioMedicine  2020 Jul;57:102862.

Dose-Independent Therapeutic Benefit of Bone Marrow Stem Cell Transplantation after MI in Mice.
Zarniko N, Skorska A, Steinhoff G, David R, Gaebel R.
Biomedicines 2020 Jun 11;8(6):157.

Single nuclei sequencing of entire mammalian hearts: strain-dependent cell-type composition and velocity.
Wolfien M, Galow AM, Müller P, Bartsch M, Brunner RM, Goldammer T, Wolkenhauer O, Hoeflich A, David R.
Cardiovasc Res 2020 Jun 1;116(7):1249-1251.

[⁶⁸Ga]-NODAGA-RGD Positron Emission Tomography (PET) for Assessment of Post Myocardial Infarction Angiogenesis as a Predictor for Left Ventricular Remodeling in Mice after Cardiac Stem Cell Therapy.
Lang CI, Döring P, Gäbel R, Vasudevan P, Lemcke H, Müller P, Stenzel J, Lindner T, Joksch M, Kurth J, Bergner C, Wester HJ, Ince H, Steinhoff G, Vollmar B, David R, Krause BJ.
Cells. 2020 May 30;9(6):1358.

¹⁸F-FDG PET-Based Imaging of Myocardial Inflammation Following Acute Myocardial Infarction in a Mouse Model.
Vasudevan P, Gäbel R, Stenzel J, Förster J, Kurth J, Vollmar B, Krause BJ, Ince H, David R, Lang CI.
Int J Mol Sci 2020 May 8;21(9):3340. 

Integrative Cluster Analysis of Whole Hearts Reveals Proliferative Cardiomyocytes in Adult Mice.
Galow AM, Wolfien M, Müller P, Bartsch M, Brunner RM, Hoeflich A, Wolkenhauer O, David R, Goldammer T.
Cells 2020 May 6;9(5):1144.

SNX27 regulates DRA activity and mediates its direct recycling by PDZ-interaction in early endosomes at the apical pole of Caco2 cells.
Bannert K, Berlin P, Reiner J, Lemcke H, David R, Engelmann R, Lamprecht G.
Am J Physiol Gastrointest Liver Physiol2020 May 1;318(5):G854-G869.

Quantitative Evaluation of the Sarcomere Network of Human hiPSC-Derived Cardiomyocytes Using Single-Molecule Localization Microscopy.
Lemcke H, Skorska A, Lang CI, Johann L, David R.
Int J Mol Sci 2020 Apr 17;21(8):2819.

GLP: A requirement in cell therapies - perspectives for the cardiovascular field.
Müller-Ruch U, Skorska A, Lemcke H, Steinhoff G, David R.
Adv Drug Deliv Rev 2020 Apr 16:S0169-409X(20)30023-5.

Cardioprotective Potential of Human Endothelial-Colony Forming Cells from Diabetic and Nondiabetic Donors.
Deutsch MA, Brunner S, Grabmaier U, David R, Ott I, Huber BC.
Cells 2020 Mar 2;9(3):588.

RNA-Based Strategies for Cardiac Reprogramming of Human Mesenchymal Stromal Cells.
Mueller P, Wolfien M, Ekat K, Lang CI, Koczan D, Wolkenhauer O, Hahn O, Peters K, Lang H, David R, Lemcke H.
Cells 2020 Feb 22;9(2):504.

Single-Nucleus Sequencing of an Entire Mammalian Heart: Cell Type Composition and Velocity.
Wolfien M, Galow AM, Müller P, Bartsch M, Brunner RM, Goldammer T, Wolkenhauer O, Hoeflich A, David R.
Cells 2020 Jan 28;9(2):318.

Angiogenic Potential of Bone Marrow Derived CD133⁺ and CD271⁺ Intramyocardial Stem Cell Trans- Plantation Post MI.
Sasse S, Skorska A, Lux CA, Steinhoff G, David R, Gaebel R.
Cells 2019 Dec 27;9(1):78.

18F-FDG PET-Based Imaging of Myocardial Inflammation Predicts a Functional Outcome Following Transplantation of mESC-Derived Cardiac Induced Cells in a Mouse Model of Myocardial Infarction.
Vasudevan P, Gaebel R, Doering P, Mueller P, Lemcke H, Stenzel J, Lindner T, Kurth J, Steinhoff G, Vollmar B, Krause BJ, Ince H, David R, Lang CI.
Cells 2019 Dec 11;8(12):1613.

Combined Coronary Artery Bypass Surgery With Bone Marrow Stem Cell Transplantation: Are We There Yet?
Ayyat KS, Argawi A, Mende M, Steinhoff G, Borger MA, Deebis AM, McCurry KR, Garbade J.
Ann Thorac Surg 2019 Dec;108(6):1913-1921.

CD271⁺ Human Mesenchymal Stem Cells Show Antiarrhythmic Effects in a Novel Murine Infarction Model.
Sadraddin H, Gaebel R, Skorska A, Lux CA, Sasse S, Ahmad B, Vasudevan P, Steinhoff G, David R.
Cells 2019 Nov 20;8(12):1474.

hiPSCs Derived Cardiac Cells for Drug and Toxicity Screening and Disease Modeling: What Micro- Electrode-Array Analyses Can Tell Us.
Kussauer S, David R, Lemcke H.
Cells 2019 Oct 28;8(11):1331.

Benefits of non-invasive methods compared to telemetry for distress analysis in a murine model of pancreatic cancer.
Kumstel S, Vasudevan P, Palme R, Zhang X, Wendt EHU, David R, Vollmar B, Zechner D.
J Adv Res 2019 Sep 14;21:35-47.

Dissecting hiPSC-CM pacemaker function in a cardiac organoid model.
Schulze ML, Lemoine MD, Fischer AW, Scherschel K, David R, Riecken K, Hansen A, Eschenhagen T, Ulmer BM.
Biomaterials 2019 Jun;206:133-145.

Therapeutic potential of menstrual blood-derived endometrial stem cells in cardiac diseases.
Liu Y, Niu R, Li W, Lin J, Stamm C, Steinhoff G, Ma N.
Cell Mol Life Sci 2019 May;76(9):1681-1695.

Nkx2.5 Based Ventricular Programming of Murine ESC-Derived Cardiomyocytes.
Thiele F, Voelkner C, Krebs V, Müller P, Jung JJ, Rimmbach C, Steinhoff G, Noack T, David R, Lemcke H.
Cell Physiol Biochem 2019;53(2):337-354.

Potential mechanisms of microRNA mobility.
Lemcke H, David R.
Traffic. 2018 Dec;19(12):910-917.

Isolation, Characterization and MicroRNA-based Genetic Modification of Human Dental Follicle Stem Cells.
Müller P, Ekat K, Brosemann A, Köntges A, David R, Lang H.
J Vis Exp 2018 Nov 16;(141).

Efficacy, Retention, and Tolerability of Brivaracetam in Patients With Epileptic Encephalopathies: A Multicenter Cohort Study From Germany.
Willems LM, Bertsche A, Bösebeck F, Hornemann F, Immisch I, Klein KM, Knake S, Kunz R, Kurlemann G, Langenbruch L, Möddel G, Müller-Schlüter K, von Podewils F, Reif PS, Steinhoff BJ, Steinig I, Rosenow F, Schubert-Bast S, Strzelczyk A.
Front Neurol. 2018 Jul 23;9:569.

Current IGFBP-Related Biomarker Research in Cardiovascular Disease-We Need More Structural and Functional Information in Clinical Studies.
Hoeflich A, David R, Hjortebjerg R.
Front Endocrinol (Lausanne) 2018 Jul 16;9:388.

Intramyocardial angiogenetic stem cells and epicardial erythropoietin save the acute ischemic heart.
Klopsch C, Skorska A, Ludwig M, Lemcke H, Maass G, Gaebel R, Beyer M, Lux C, Toelk A, Müller K, Maschmeier C, Rohde S, Mela P, Müller-Hilke B, Jockenhoevel S, Vollmar B, Jaster R, David R, Steinhoff G.
Dis Model Mech 2018 Jun 22;11(6):dmm033282.

Protocol for MicroRNA Transfer into Adult Bone Marrow-derived Hematopoietic Stem Cells to Enable Cell Engineering Combined with Magnetic Targeting.
Hausburg F, Müller P, Voronina N, Steinhoff G, David R.
J Vis Exp 2018 Jun 18;(136):57474.

Predictors of colonization with Staphylococcus species among patients scheduled for cardiac and orthopedic interventions at tertiary care hospitals in north-eastern Germany-a prevalence screening study.
Neidhart S, Zaatreh S, Klinder A, Redanz S, Spitzmüller R, Holtfreter S, Warnke P, Alozie A, Henck V, Göhler A, Ellenrieder M, AbouKoura M, Divchev D, Gümbel D, Napp M, Steinhoff G, Nienaber C, Ekkernkamp A, Mittelmeier W, Güthoff C, Podbielski A, Stengel D, Bader R.
Eur J Clin Microbiol Infect Dis 2018 Apr;37(4):633-641.

Smell of cells: Volatile profiling of stem- and non-stem cell proliferation.
Bischoff AC, Oertel P, Sukul P, Rimmbach C, David R, Schubert J, Miekisch W.
J Breath Res 2018 Mar 1;12(2):026014.

Recent Progress in Stem Cell Modification for Cardiac Regeneration.
Lemcke H, Voronina N, Steinhoff G, David R
Stem Cells Int 2018 Jan 16;2018:1909346.

Stem Cell Therapy in Heart Diseases - Cell Types, Mechanisms and Improvement Strategies.
Müller P, Lemcke H, David R
Cell Physiol Biochem. 2018;48(6):2607-2655.

Specific Cell (Re-)Programming: Approaches and Perspectives.
Hausburg F, Jung JJ, David R.
Adv Biochem Eng Biotechnol. 2018;163:71-115.

Vimentin-Induced Cardiac Mesenchymal Stem Cells Proliferate in the Acute Ischemic Myocardium.
Klopsch C, Gaebel R, Lemcke H, Beyer M, Vasudevan P, Fang HY, Quante M, Vollmar B, Skorska A, David R, Steinhoff G.
Cells Tissues Organs. 2018;206(1-2):35-45.

Conventional Surgery for Early and Late Symptomatic Mitral Valve Stenosis After MitraClip^® Intervention: An Institutional Experience With Four Consecutive Patients.
Alozie A, Paranskaya L, Westphal B, Kaminski A, Steinhoff G, Sherif M, Ince H, Öner A.
Heart Lung Circ. 2017 Dec;26(12):1330-1338.

Mammalian γ2 AMPK regulates intrinsic heart rate.
Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV, Sharpe EJ, Wolfien M, Czibik G, Steeples V, Ghaffari S, Nguyen C, Stockenhuber A, Clair JRS, Rimmbach C, Okamoto Y, Yang D, Wang M, Ziman BD, Moen JM, Riordon DR, Ramirez C, Paina M, Lee J, Zhang J, Ahmet I, Matt MG, Tarasova YS, Baban D, Sahgal N, Lockstone H, Puliyadi R, de Bono J, Siggs OM, Gomes J, Muskett H, Maguire ML, Beglov Y, Kelly M, Dos Santos PPN, Bright NJ, Woods A, Gehmlich K, Isackson H, Douglas G, Ferguson DJP, Schneider JE, Tinker A, Wolkenhauer O, Channon KM, Cornall RJ, Sternick EB, Paterson DJ, Redwood CS, Carling D, Proenza C, David R, Baruscotti M, DiFrancesco D, Lakatta EG, Watkins H, Ashrafian H.
Nat Commun. 2017 Nov 2;8(1):1258.

Stem cells and heart disease - Brake or accelerator?
Steinhoff G, Nesteruk J, Wolfien M, Große J, Ruch U, Vasudevan P, Müller P.
Adv Drug Deliv Rev. 2017 Oct 1;120:2-24.

(Re-)programming of subtype specific cardiomyocytes.
Hausburg F, Jung JJ, Hoch M, Wolfien M, Yavari A, Rimmbach C, David R.
Adv Drug Deliv Rev. 2017 Oct 1;120:142-167.

The enigma of stem cell-based therapies - how to conquer the death valley of therapy development.
Steinhoff G.
Adv Drug Deliv Rev. 2017 Oct 1;120:1.

Safety of Simultaneous Coronary Artery Bypass Grafting and Carotid Endarterectomy Versus Isolated Coronary Artery Bypass Grafting: A Randomized Clinical Trial.
Weimar C, Bilbilis K, Rekowski J, Holst T, Beyersdorf F, Breuer M, Dahm M, Diegeler A, Kowalski A, Martens S, Mohr FW, Ondrášek J, Reiter B, Roth P, Seipelt R, Siggelkow M, Steinhoff G, Moritz A, Wilhelmi M, Wimmer-Greinecker G, Diener HC, Jakob H, Ose C, Scherag A, Knipp SC; CABACS Trial Investigators.
Stroke. 2017 Oct;48(10):2769-2775.

Mechanisms of stem cell based cardiac repair-gap junctional signaling promotes the cardiac lineage specification of mesenchymal stem cells.
Lemcke H, Gaebel R, Skorska A, Voronina N, Lux CA, Petters J, Sasse S, Zarniko N, Steinhoff G, David R.
Sci Rep. 2017 Aug 29;7(1):9755.

Cardiac Function Improvement and Bone Marrow Response -: Outcome Analysis of the Randomized PERFECT Phase III Clinical Trial of Intramyocardial CD133⁺ Application After Myocardial Infarction.
Steinhoff G, Nesteruk J, Wolfien M, Kundt G; PERFECT Trial Investigators Group, Börgermann J, David R, Garbade J, Große J, Haverich A, Hennig H, Kaminski A, Lotz J, Mohr FW, Müller P, Oostendorp R, Ruch U, Sarikouch S, Skorska A, Stamm C, Tiedemann G, Wagner FM, Wolkenhauer O.
EBioMedicine. 2017 Aug;22:208-224.

Intramyocardial fate and effect of iron nanoparticles co-injected with MACS^® purified stem cell products.
Müller P, Gaebel R, Lemcke H, Wiekhorst F, Hausburg F, Lang C, Zarniko N, Westphal B, Steinhoff G, David R.
Biomaterials. 2017 Aug;135:74-84.

Therapeutic progenitor cell application for tissue regeneration: Analyzing the impact of toll-like receptor signaling on c-kit⁺ cell migration following ischemia-reperfusion injury in vivo.
Donndorf P, Abubaker S, Vollmar B, Rimmbach C, Steinhoff G, Kaminski A.
Microvasc Res. 2017 Jul;112:87-92.

Data on the fate of MACS® MicroBeads intramyocardially co-injected with stem cell products.
Müller P, Gaebel R, Lemcke H, Steinhoff G, David R.
Data Brief. 2017 Jun 24;13:569-574.

Analysis of the Gap Junction-dependent Transfer of miRNA with 3D-FRAP Microscopy.
Lemcke H, Voronina N, Steinhoff G, David R.
J Vis Exp. 2017 Jun 19;(124):55870.

Preparation and In Vitro Characterization of Magnetized miR-modified Endothelial Cells.
Voronina N, Lemcke H, Wiekhorst F, Kühn JP, Frank M, Steinhoff G, David R.
J Vis Exp. 2017 May 2;(123):55567.

Clinical outcomes of conventional surgery versus MitraClip® therapy for moderate to severe symptomatic mitral valve regurgitation in the elderly population: an institutional experience.
Alozie A, Paranskaya L, Westphal B, Kaminski A, Sherif M, Sindt M, Kische S, Schubert J, Diedrich D, Ince H, Steinhoff G, Öner A.
BMC Cardiovasc Disord. 2017 Mar 20;17(1):85.

GMP-conformant on-site manufacturing of a CD133⁺ stem cell product for cardiovascular regeneration.
Skorska A, Müller P, Gaebel R, Große J, Lemcke H, Lux CA, Bastian M, Hausburg F, Zarniko N, Bubritzki S, Ruch U, Tiedemann G, David R, Steinhoff G.
Stem Cell Res Ther. 2017 Feb 10;8(1):33.

Cardiac Mesenchymal Stem Cells Proliferate Early in the Ischemic Heart.
Klopsch C, Skorska A, Ludwig M, Gaebel R, Lemcke H, Kleiner G, Beyer M, Vollmar B, David R, Steinhoff G.
Eur Surg Res. 2017;58(5-6):341-353.

Thymosin β4 Improves Differentiation and Vascularization of EHTs.
Ziegler T, Hinkel R, Stöhr A, Eschenhagen T, Laugwitz KL, le Noble F, David R, Hansen A, Kupatt C.
Stem Cells Int. 2017;2017:6848271.

Cardiac Cell Therapies for the Treatment of Acute Myocardial Infarction: A Meta-Analysis from Mouse Studies.
Lang CI, Wolfien M, Langenbach A, Müller P, Wolkenhauer O, Yavari A, Ince H, Steinhoff G, Krause BJ, David R, Glass Ä.
Cell Physiol Biochem. 2017;42(1):254-268.

Non-viral magnetic engineering of endothelial cells with microRNA and plasmid-DNA-An optimized targeting approach.
Voronina N, Lemcke H, Wiekhorst F, Kühn JP, Rimmbach C, Steinhoff G, David R.
Nanomedicine. 2016 Nov;12(8):2353-2364.

Applying 3D-FRAP microscopy to analyse gap junction-dependent shuttling of small antisense RNAs between cardiomyocytes.
Lemcke H, Peukert J, Voronina N, Skorska A, Steinhoff G, David R.
J Mol Cell Cardiol. 2016 Sep;98:117-27.

Cardiac FDG-PET: a straight forward tool with high potential.
Lang CI, Krause BJ, David R.
Eur Heart J Cardiovasc Imaging.2016 Feb;17(2):130-1.

TRAPLINE: a standardized and automated pipeline for RNA sequencing data analysis, evaluation and annotation.
Wolfien M, Rimmbach C, Schmitz U, Jung JJ, Krebs S, Steinhoff G, David R, Wolkenhauer O.
BMC Bioinformatics. 2016 Jan 6;17:21.

Magnet-Bead Based MicroRNA Delivery System to Modify CD133⁺ Stem Cells.
Müller P, Voronina N, Hausburg F, Lux CA, Wiekhorst F, Steinhoff G, David R.
Stem Cells Int. 2016;2016:7152761.

Cardiac Hypertrophy: An Introduction to Molekular and Cellular Basis

Past and Present of Total Artificial Heart Therapy: A Success Story.
Samak M, Fatullayev J, Sabashnikov A, Zeriouh M, Rahmanian PB, Choi YH, Wippermann J, Wahlers T, Schmack B, Ruhparwar A, Dohmen PM, Karck M, Popov AF, Simon AR, Weymann A.
Med Sci Monit Basic Res. 2015 Sep 7;21:183-90. doi: 10.12659/MSMBR.895418. PMID: 26343363 Free PMC article. Review.

Combination of European System for Cardiac Operative Risk Evaluation (EuroSCORE) and Cardiac Surgery Score (CASUS) to Improve Outcome Prediction in Cardiac Surgery.
Doerr F, Heldwein MB, Bayer O, Sabashnikov A, Weymann A, Dohmen PM, Wahlers T, Hekmat K.
Med Sci Monit Basic Res. 2015 Aug 17;21:172-8. doi: 10.12659/MSMBR.895004. PMID: 26279053 Free PMC article.

Non-Heart-Beating Donor Heart Transplantation: Breaking the Taboo.
Fatullayev J, Samak M, Sabashnikov A, Weymann A, Mohite PN, García-Sáez D, Patil NP, Dohmen PM, Popov AF, Simon AR, Zeriouh M.
Med Sci Monit Basic Res. 2015 Jul 15;21:153-6. doi: 10.12659/MSMBR.894985. PMID: 26174972 Free PMC article. Review.

Daptomycin for the Treatment of Infective Endocarditis: Results from European Cubicin(®) Outcomes Registry and Experience (EU-CORE).
Guleri A, Utili R, Dohmen P, Petrosillo N, Piper C, Pathan R, Hamed K.
Infect Dis Ther. 2015 Sep;4(3):283-96. doi: 10.1007/s40121-015-0075-9. Epub 2015 Jul 14. PMID: 26168988 Free PMC article.

Inclusion of 'ICU-Day' in a Logistic Scoring System Improves Mortality Prediction in Cardiac Surgery.
Doerr F, Heldwein MB, Bayer O, Sabashnikov A, Weymann A, Dohmen PM, Wahlers T, Hekmat K.
Med Sci Monit Basic Res. 2015 Jul 3;21:145-52. doi: 10.12659/MSMBR.895003. PMID: 26137928 Free PMC article.

Continuous-Flow Left Ventricular Assist Device Thrombosis: A Danger Foreseen is a Danger Avoided.
Fatullayev J, Samak M, Sabashnikov A, Zeriouh M, Rahmanian PB, Choi YH, Schmack B, Kallenbach K, Ruhparwar A, Eghbalzadeh K, Dohmen PM, Karck M, Wippermann J, Wahlers T, Popov AF, Simon AR, Weymann A.
Med Sci Monit Basic Res. 2015 Jul 1;21:141-4. doi: 10.12659/MSMBR.894840. PMID: 26250695 Free PMC article. Review.

Injectable tissue engineered pulmonary heart valve implantation into the pig model: A feasibility study.
Schlegel F, Salameh A, Oelmann K, Halling M, Dhein S, Mohr FW, Dohmen PM.
Med Sci Monit Basic Res. 2015 Jun 24;21:135-40. doi: 10.12659/MSMBR.894838. PMID: 26104851 Free PMC article.

Autocrine control of angiogenesis by endogenous acetylcholine in an in vitro model using human endothelial cells: evidence for an autocrine cholinergic system in endothelial cells.
Dhein S, Wermke A, von Salisch S, Schlegel F, Stepan H, Dohmen PM, Kostelka M, Mohr FW.
J Cardiovasc Pharmacol. 2015 May;65(5):508-15. doi: 10.1097/FJC.0000000000000221. PMID: 25636069

Position of totally thoracoscopic surgical ablation in the treatment of atrial fibrillation: an alternative method of conduction testing.
Sabashnikov A, Weymann A, Haldar S, Soliman RF, Fatullayev J, Jones D, Hussain W, Choi YH, Zeriouh M, Dohmen PM, Popov AF, Markides V, Wong T, Bahrami T.
Med Sci Monit Basic Res. 2015 Apr 23;21:76-80. doi: 10.12659/MSMBR.894239. PMID: 25904211 Free PMC article. Review.

Utilization of the organ care system - a game-changer in combating donor organ shortage.
Popov AF, García Sáez D, Sabashnikov A, Patil NP, Zeriouh M, Mohite PN, Zych B, Schmack B, Ruhparwar A, Kallenbach K, Dohmen PM, Karck M, Simon AR, Weymann A.
Med Sci Monit Basic Res. 2015 Mar 12;21:29-32. doi: 10.12659/MSMBR.894020. PMID: 25761708 Free PMC article. Review.

Does prolonged post-mortem cold ischemic harvesting time influence cryopreserved pulmonary homograft tissue integrity?
Smit FE, Bester D, van den Heever JJ, Schlegel F, Botes L, Dohmen PM.
Cell Tissue Bank. 2015 Dec;16(4):531-44. doi: 10.1007/s10561-015-9500-2. Epub 2015 Feb 8. PMID: 25663640

Ex vivo lung perfusion - state of the art in lung donor pool expansion.
Popov AF, Sabashnikov A, Patil NP, Zeriouh M, Mohite PN, Zych B, Saez DG, Schmack B, Ruhparwar A, Dohmen PM, Karck M, Simon AR, Weymann A.
Med Sci Monit Basic Res. 2015 Feb 3;21:9-14. doi: 10.12659/MSMBR.893674. PMID: 25644463 Free PMC article. Review.

Cardiovascular tissue engineering: where we come from and where are we now?
Smit FE, Dohmen PM.
Med Sci Monit Basic Res. 2015 Jan 27;21:1-3. doi: 10.12659/MSMBR.893546. PMID: 25623227 Free PMC article. Review.

Risk and Outcome of Aortic Valve Surgery in the Transcatheter Valve Era: The Gender Aspect.
Heinze G, Christ T, Leonards CO, Dohmen PM, Konertz W.
Ann Thorac Cardiovasc Surg. 2015;21(5):446-51. doi: 10.5761/atcs.oa.14-00291. Epub 2015 May 25. PMID: 26004109 Free PMC article.

Benefits of sutureless aortic valves may not be limited to reduced crossclamp time.
Dohmen PM.
J Thorac Cardiovasc Surg. 2015 Jan;149(1):395. doi: 10.1016/j.jtcvs.2014.09.032. PMID: 25524692 No abstract available.

Outcome of aortic valve replacement for active infective endocarditis in patients on chronic hemodialysis.
Dohmen PM, Binner C, Mende M, Bakhtiary F, Etz C, Pfannmüller B, Davierwala P, Borger MA, Misfeld M, Mohr FW.
Ann Thorac Surg. 2015 Feb;99(2):532-8. doi: 10.1016/j.athoracsur.2014.08.025. Epub 2014 Dec 4. PMID: 25483000

A randomized multicenter trial of minimally invasive rapid deployment versus conventional full sternotomy aortic valve replacement.
Borger MA, Moustafine V, Conradi L, Knosalla C, Richter M, Merk DR, Doenst T, Hammerschmidt R, Treede H, Dohmen P, Strauch JT.
Ann Thorac Surg. 2015 Jan;99(1):17-25. doi: 10.1016/j.athoracsur.2014.09.022. Epub 2014 Nov 20. PMID: 25441065 Clinical Trial.

Minimal invasive aortic valve replacement surgery is associated with improved survival: a propensity-matched comparison.
Merk DR, Lehmann S, Holzhey DM, Dohmen P, Candolfi P, Misfeld M, Mohr FW, Borger MA.
Eur J Cardiothorac Surg. 2015 Jan;47(1):11-7; discussion 17. doi: 10.1093/ejcts/ezu068. Epub 2014 Mar 5. PMID: 24599160

Gap junctional shuttling of miRNA--A novel pathway of intercellular gene regulation and its prospects in clinical application.
Lemcke H, Steinhoff G, David R.
Cell Signal. 2015 Dec;27(12):2506-14.

(124)I-PET Assessment of Human Sodium Iodide Symporter Reporter Gene Activity for Highly Sensitive In Vivo Monitoring of Teratoma Formation in Mice.
Lehner S, Lang C, Kaissis G, Todica A, Zacherl MJ, Boening G, Spitzweg C, Herbach N, Franz WM, Krause BJ, Steinhoff G, Bartenstein P, Hacker M, David R.
Mol Imaging Biol. 2015 Dec;17(6):874-83.

Spray- and laser-assisted biomaterial processing for fast and efficient autologous cell-plus-matrix tissue engineering.
Klopsch C, Gäbel R, Kaminski A, Mark P, Wang W, Toelk A, Delyagina E, Kleiner G, Koch L, Chichkov B, Mela P, Jockenhoevel S, Ma N, Steinhoff G.
J Tissue Eng Regen Med. 2015 Dec;9(12):E177-90.

Streptococcus bovis infectious endocarditis and occult gastrointestinal neoplasia: experience with 25 consecutive patients treated surgically.
Alozie A, Köller K, Pose L, Raftis M, Steinhoff G, Westphal B, Lamprecht G, Podbielski A.
Gut Pathog. 2015 Oct 15;7:27.

Adjunctive surgical atrial fibrillation ablation during cardiac surgery: real life experiences.
Tischer TS, Schneider R, Lauschke J, Nesselmann C, Steinhoff G, Bänsch D.Herzschrittmacherther
Elektrophysiol. 2015 Sep;26(3):291-6.

Do oral bacteria alter the regenerative potential of stem cells? A concise review.
Chatzivasileiou K, Kriebel K, Steinhoff G, Kreikemeyer B, Lang H.
J Cell Mol Med. 2015 Sep;19(9):2067-74.

Cardiac Function Improvement and Bone Marrow Response -: Outcome Analysis of the Randomized PERFECT Phase III Clinical Trial of Intramyocardial CD133⁺ Application After Myocardial Infarction.
Steinhoff G, Nesteruk J, Wolfien M, Kundt G; PERFECT Trial Investigators Group, Börgermann J, David R, Garbade J, Große J, Haverich A, Hennig H, Kaminski A, Lotz J, Mohr FW, Müller P, Oostendorp R, Ruch U, Sarikouch S, Skorska A, Stamm C, Tiedemann G, Wagner FM, Wolkenhauer O.
EBioMedicine. 2017 Aug;22:208-224.

The CD4(+) AT2R(+) T cell subpopulation improves post-infarction remodelling and restores cardiac function.
Skorska A, von Haehling S, Ludwig M, Lux CA, Gaebel R, Kleiner G, Klopsch C, Dong J, Curato C, Altarche-Xifró W, Slavic S, Unger T, Steinhoff G, Li J, David R.
J Cell Mol Med. 2015 Aug;19(8):1975-85.

Generation of murine cardiac pacemaker cell aggregates based on ES-cell-programming in combination with Myh6-promoter-selection.
Rimmbach C, Jung JJ, David R.
J Vis Exp. 2015 Feb 17;(96):e52465.

Exploiting AT2R to Improve CD117 Stem Cell Function In Vitro and In Vivo--Perspectives for Cardiac Stem Cell Therapy.
Ludwig M, Tölk A, Skorska A, Maschmeier C, Gaebel R, Lux CA, Steinhoff G, David R.
Cell Physiol Biochem. 2015;37(1):77-93.

Impact of short-term liquid storage on human CD133(+) stem cells.
Lux CA, Mark P, Klopsch C, Laupheimer M, Tu-Rapp H, Li W, Ma N, Steinhoff G, David R.
Cell Transplant. 2015;24(11):2409-22.

Defining optimized properties of modified mRNA to enhance virus- and DNA- independent protein expression in adult stem cells and fibroblasts.
Hausburg F, Na S, Voronina N, Skorska A, Müller P, Steinhoff G, David R.
Cell Physiol Biochem. 2015;35(4):1360-71.

Mesenchymal stem cell therapy in nonhematopoietic diseases.
de Carvalho KA, Steinhoff G, Chachques JC.
Stem Cells Int. 2015;2015:676903.

Mobilization of Bone Marrow-Derived Endothelial Progenitor Cells following Finnish Sauna: A Pilot Study.
Donndorf P, Lube L, Lux C, Skorska A, Steinhoff G, Kraft K.
Forsch Komplementmed. 2015;22(4):246-50.

In-vivo comparison of the acute retention of stem cell derivatives and fibroblasts after intramyocardial transplantation in the mouse model.
Lang C, Lehner S, Todica A, Boening G, Zacherl M, Franz WM, Krause BJ, Bartenstein P, Hacker M, David R.
Eur J Nucl Med Mol Imaging. 2014 Dec;41(12):2325-36.

Awake extracorporeal membrane oxygenation (ECMO) as bridge to recovery after left main coronary artery occlusion: a promising concept of haemodynamic support in cardiogenic shock.
Alozie A, Kische S, Birken T, Kaminski A, Westphal B, Nöldge-Schomburg G, Ince H, Steinhoff G.
Heart Lung Circ. 2014 Oct;23(10):e217-21.

Impact of closed minimal extracorporeal circulation on microvascular tissue perfusion during surgical aortic valve replacement: intravital imaging in a prospective randomized study.
Donndorf P, Park H, Vollmar B, Alms A, Gierer P, Steinhoff G, Kaminski A.
Interact Cardiovasc Thorac Surg. 2014 Aug;19(2):211-7.

Surgical revision after percutaneous mitral valve repair by edge-to-edge device: when the strategy fails in the highest risk surgical population.
Alozie A, Westphal B, Kische S, Kaminski A, Paranskaya L, Bozdag-Turan I, Ortak J, Schubert J, Steinhoff G, Ince H.
Eur J Cardiothorac Surg. 2014 Jul;46(1):55-60.

Improved transfection in human mesenchymal stem cells: effective intracellular release of pDNA by magnetic polyplexes.
Delyagina E, Schade A, Scharfenberg D, Skorska A, Lux C, Li W, Steinhoff G.
Nanomedicine (Lond). 2014 May;9(7):999-1017.

Programming and isolation of highly pure physiologically and pharmacologically functional sinus-nodal bodies from pluripotent stem cells.
Jung JJ, Husse B, Rimmbach C, Krebs S, Stieber J, Steinhoff G, Dendorfer A, Franz WM, David R.
Stem Cell Reports. 2014 Apr 17;2(5):592-605.

Control of IGFBP-2 Expression by Steroids and Peptide Hormones in Vertebrates.
Hoeflich A, Wirthgen E, David R, Classen CF, Spitschak M, Brenmoehl J.
Front Endocrinol (Lausanne). 2014 Apr 7;5:43.

Re-growth of the adult heart by stem cells?
Steinhoff G.
Eur J Cardiothorac Surg. 2014 Jan;45(1):6-9.

Selective Migration of Subpopulations of Bone Marrow Cells along an SDF-1α and ATP Gradient.
Laupheimer M, Skorska A, Große J, Tiedemann G, Steinhoff G, David R, Lux CA.
Bone Marrow Res. 2014;2014:182645.

Magnetic Nanoparticle Based Nonviral MicroRNA Delivery into Freshly Isolated CD105(+) hMSCs.
Schade A, Müller P, Delyagina E, Voronina N, Skorska A, Lux C, Steinhoff G, David R.
Stem Cells Int. 2014;2014:197154.

Intravital microscopy of the microcirculation in the mouse cremaster muscle for the analysis of peripheral stem cell migration.
Donndorf P, Ludwig M, Wildschütz F, Useini D, Kaminski A, Vollmar B, Steinhoff G.
J Vis Exp. 2013 Nov 5;(81):e50485.

Surgical double valve replacement after transcatheter aortic valve implantation and interventional mitral valve repair.
Wendeborn J, Donndorf P, Westphal B, Steinhoff G.
Interact Cardiovasc Thorac Surg. 2013 Nov;17(5):909-11.

Positron emission tomography based in-vivo imaging of early phase stem cell retention after intramyocardial delivery in the mouse model.
Lang C, Lehner S, Todica A, Boening G, Franz WM, Bartenstein P, Hacker M, David R.
Eur J Nucl Med Mol Imaging. 2013 Oct;40(11):1730-8.

Characterization of ion currents of murine CD117(pos) stem cells in vitro and their modulation under AT2 R stimulation.
Ludwig M, Skorska A, Tölk A, Hopp HH, Patejdl R, Li J, Steinhoff G, Noack T.
Acta Physiol (Oxf). 2013 Jul;208(3):274-87.

Dental follicle progenitor cells responses to Porphyromonas gingivalis LPS.
Chatzivasileiou K, Lux CA, Steinhoff G, Lang H.
J Cell Mol Med. 2013 Jun;17(6):766-73.

Innovative strategy for microRNA delivery in human mesenchymal stem cells via magnetic nanoparticles.
Schade A, Delyagina E, Scharfenberg D, Skorska A, Lux C, David R, Steinhoff G.
Int J Mol Sci. 2013 May 23;14(6):10710-26.

The road from systems biology to systems medicine.
Wolkenhauer O, Auffray C, Jaster R, Steinhoff G, Dammann O.
Pediatr Res. 2013 Apr;73(4 Pt 2):502-7.

Asymptomatic blood cyst of the papillary muscle in an adult undergoing coronary bypass surgery.
Donndorf P, Bermaoui B, Westphal B, Steinhoff G.
Interact Cardiovasc Thorac Surg. 2013 Mar;16(3):402-4.

Selection of a common multipotent cardiovascular stem cell using the 3.4-kb MesP1 promoter fragment.
David R, Schwarz F, Rimmbach C, Nathan P, Jung J, Brenner C, Jarsch V, Stieber J, Franz WM.
Basic Res Cardiol. 2013 Jan;108(1):312.

CD133-Positive Cells for Cardiac Stem Cell Therapy: Current Status and Outlook.
Donndorf P, Steinhoff G.
Adv Exp Med Biol. 2013;777:215-27.

Analyzing migratory properties of human CD133(+) stem cells in vivo after intraoperative sternal bone marrow isolation.
Donndorf P, Useini D, Lux CA, Vollmar B, Delyagina E, Laupheimer M, Kaminski A, Steinhoff G.
Cell Transplant. 2013;22(9):1627-35.

Human Mesenchymal Stem Cells Display Reduced Expression of CD105 after Culture in Serum-Free Medium.
Mark P, Kleinsorge M, Gaebel R, Lux CA, Toelk A, Pittermann E, David R, Steinhoff G, Ma N.
Stem Cells Int. 2013;2013:698076.

Stem cell therapy for the treatment of acute myocardial infarction and chronic ischemic heart disease.
Donndorf P, Strauer BE, Haverich A, Steinhoff G.
Curr Pharm Biotechnol. 2013;14(1):12-9.

Non-viral gene delivery methods.
Wang W, Li W, Ma N, Steinhoff G.
Curr Pharm Biotechnol. 2013;14(1):46-60.

Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator.
Kubota R, Boman NL, David R, Mallikaarjun S, Patil S, Birch D.
Retina. 2012 Jan;32(1):183-8. doi: 10.1097/IAE.0b013e318217369e. PMID: 21519291 Clinical Trial.

oxLDL downregulates the dendritic cell homing factors CCR7 and CCL21.
Nickel T, Pfeiler S, Summo C, Kopp R, Meimarakis G, Sicic Z, Lambert M, Lackermair K, David R, Beiras-Fernandez A, Kaczmarek I, Weis M.
Mediators Inflamm. 2012;2012:320953. doi: 10.1155/2012/320953. Epub 2012 Apr 30. PMID: 22619482 Free PMC article.

Cadherin-dependent differential cell adhesion in Xenopus causes cell sorting in vitro but not in the embryo.
Ninomiya H, David R, Damm EW, Fagotto F, Niessen CM, Winklbauer R.
J Cell Sci. 2012 Apr 15;125(Pt 8):1877-83. doi: 10.1242/jcs.095315. Epub 2012 Feb 10. PMID: 22328523

From pluripotency to distinct cardiomyocyte subtypes.
David R, Franz WM.
Physiology (Bethesda). 2012 Jun;27(3):119-29. doi: 10.1152/physiol.00044.2011. PMID: 22689787 Free article. Review.

Bilateral tension pneumothoraces leading to cardiac arrest after coronary artery bypass surgery.
Alozie A, Westphal B, Yerebakan C, Steinhoff G.
Thorac Cardiovasc Surg. 2012 Dec;60 Suppl 2:e6-8.

Comparing microvascular alterations during minimal extracorporeal circulation and conventional cardiopulmonary bypass in coronary artery bypass graft surgery: a prospective, randomized study.
Donndorf P, Kühn F, Vollmar B, Rösner J, Liebold A, Gierer P, Steinhoff G, Kaminski A.
J Thorac Cardiovasc Surg. 2012 Sep;144(3):677-83.

Erythropoietin attenuates the sequels of ischaemic spinal cord injury with enhanced recruitment of CD34+ cells in mice.
Hirano K, Wagner K, Mark P, Pittermann E, Gäbel R, Furlani D, Li W, Vollmar B, Yamada T, Steinhoff G, Ma N.
J Cell Mol Med. 2012 Aug;16(8):1792-802.

Validating intramyocardial bone marrow stem cell therapy in combination with coronary artery bypass grafting, the PERFECT Phase III randomized multicenter trial: study protocol for a randomized controlled trial.
Donndorf P, Kaminski A, Tiedemann G, Kundt G, Steinhoff G.
Trials. 2012 Jul 2;13:99.

Surgical revision after percutaneous mitral valve repair by edge-to-edge device: when the strategy fails in the highest risk surgical population.
Alozie A, Westphal B, Kische S, Kaminski A, Paranskaya L, Bozdag-Turan I, Ortak J, Schubert J, Steinhoff G, Ince H.
Eur J Cardiothorac Surg. 2014 Jul;46(1):55-60.

HMGB-1 induces c-kit+ cell microvascular rolling and adhesion via both toll-like receptor-2 and toll-like receptor-4 of endothelial cells.
Furlani D, Donndorf P, Westien I, Ugurlucan M, Pittermann E, Wang W, Li W, Vollmar B, Steinhoff G, Kaminski A, Ma N.
J Cell Mol Med. 2012 May;16(5):1094-105.

Culture-negative infective endocarditis of the aortic valve due to Aerococcus urinae: a rare aetiology.
Alozie A, Yerebakan C, Westphal B, Steinhoff G, Podbielski A.
Heart Lung Circ. 2012 Apr;21(4):231-3.

In-hospital outcome of patients with severe mitral valve regurgitation classified as inoperable and treated with the MitraClip® device.
Divchev D, Kische S, Paranskaya L, Schneider H, Rehders T, Ortak J, Akin I, Turan G, Turan CH, Steinhoff G, Nöldge-Schomburg G, Nienaber CA, Ince H.
J Interv Cardiol. 2012 Apr;25(2):180-9.

Update on cardiac stem cell therapy in heart failure.
Donndorf P, Strauer BE, Steinhoff G.
Curr Opin Cardiol. 2012 Mar;27(2):154-60.

Congenital quadricuspid aortic valve: a rare valvular pathology leading to aortic valve insufficiency.
Alozie A, Kaminski A, Donndorf P, Westphal B, Steinhoff G.
Heart Lung Circ. 2012 Mar;21(3):193.

The regenerative potential of angiotensin AT2 receptor in cardiac repair.
Ludwig M, Steinhoff G, Li J.
Can J Physiol Pharmacol. 2012 Mar;90(3):287-93.

Transient ischaemic attack due to the lead of an implantable defibrillator in the left heart.
Alozie A, Westphal B, Yerebakan C, Steinhoff G.
Interact Cardiovasc Thorac Surg. 2012 Jan;14(1):128-30.

Targeted delivery of human VEGF gene via complexes of magnetic nanoparticle-adenoviral vectors enhanced cardiac regeneration.
Zhang Y, Li W, Ou L, Wang W, Delyagina E, Lux C, Sorg H, Riehemann K, Steinhoff G, Ma N.
PLoS One. 2012;7(7):e39490.

Tissue-engineered devices in cardiovascular surgery.
Klopsch C, Steinhoff G.
Eur Surg Res. 2012;49(1):44-52.